上榜理由:医德高尚,这是他的真实评价,医术金民,这是病友送给他的赞美。陈伟良专注于口腔颌面外科疾病诊治,颞下颌关节疾病综合治疗、口腔颌面肿瘤诊治、口腔颌面部整形。参编十多部专著,获广东省科学技术进步奖二等奖2项。从医经验丰富,医术回春,好评颇高。在患者眼中,他是一名医术高明,耐心敬业的好医生。
所属医院:中山大学孙逸仙纪念医院
所属科室:口腔科
医生职称:教授 主任医师
擅长疾病: 对口腔颅颌面-头颈部良性(如颌骨囊肿,鳃裂囊肿,腮腺混合瘤,成釉细胞瘤等)和恶性肿瘤(舌癌,牙龈癌,颊癌,腭癌,舌根癌等口腔口咽癌和颌面颌骨肉瘤)在分子水平方面作深入的研究。对良恶性肿瘤手术治疗,软硬组织缺损修复以及中晚期口腔癌化学治疗、基因靶向治疗和免疫治疗等综合治疗;口腔颌面部脉管疾病-血管瘤,淋巴管瘤,脉管畸形的基础研究。治疗包括手术、超选择性栓塞、放射、硬化、核素和冷冻等综合治疗;口腔颌面部外伤骨折救治;口腔颌面部感染的治疗;口腔颌面部先天(唇腭裂和颌骨畸形)后天畸形(外伤疤痕和缺损)整复;颌骨前突或后缩畸形整复和口腔颅颌面痛症和神经精神疾病的诊断和治疗等有较深造诣。
介绍:
口腔科教授、主任医师、博士生导师,现任口腔科主任。自1983年中山医科大学口腔医学系毕业以来一直在中山大学附属第二医院口腔颌面外科从事医疗、教学和科研工作。1990年晋升为讲师,主治医师;1995年破格晋升为副主任医师,1996年转评为副教授,硕士研究生导师;2000年晋升教授,主任医师。1994年至1997年任口腔科副主任,1997年至2000年任口腔科主任,2001年至2003年任中山大学颅颌面外科中心副主任兼中山二院南院副院长。2005年至2007年任中山大学颅颌面外科中心副主任兼附属第二医院口腔颌面外科主任。2007年竟聘上三级教授,2008年至今任中山大学颅颌面外科中心主任兼孙逸仙纪念医院口腔科主任。2011年作为口腔颌面外科学科带头人,主持申报国家重点临床专科(口腔颌面外科)学科带头人获得成功,并带领口腔颌面外科团队开展工作。
学习工作经历:
1983年中山医科大学口腔医学系毕业,1987年中山医科大学高级英语班培训,1998年美国加州大学(UCLA)客座教授, 在美研修口腔颌面外科,2003年在澳大利亚皇家儿童医院研修颅颌面外科,2005年中山大学岭南(大学)学院高级工商管理班毕业,获h-EMBA学位。
学会、杂志兼职:
广东省医学会颌面-头颈外科学分会主任委员。国际口腔颌面外科协会会员和国际口腔癌协会会员。国际口腔医学杂志、中国口腔颌面外科杂志和中国实用口腔科杂志编委;国际著名杂志Cancer, Cancer Biomarkers, Head & Neck,International Journal of Oral & Maxillofacial Surgery, Oral Oncology, World Journal of Surgical Oncology,Journal of Oral Pathology and Medicine, European Surgical Research, Clinical Anatomy, Saudi Medical Journal, European Surgical Research, International Journal of Otolaryngology, International Journal of Pediatric Otorhinolaryngology, Journal of Pediatric Surgery,Annals of Medical and Health Sciences Research, Indian Journal of Dental Research, Open Journal of Stomatology, 中华医学杂志, Chinese Journal of Dental Research,中山大学学报(医科版)和中国口腔颌面外科杂志等国内外著名杂志的审稿专家,以及2011年版《中文核心期刊要目总览》评审专家。
临床工作:
作为国家重点临床专科-口腔颌面外科学科带头人,中山大学颅颌面外科中心主任和中山大学孙逸仙纪念医院口腔科主任,30年来一直在颅颌面口腔-头颈外科临床第一线,全心全意为病人服务,医术精湛。
教学工作:
2003年~2013年主持国家级继续教育项目—《口腔颌面-头颈肿瘤预防和综合治疗高级研修班》,1998年至2013年指导口腔颌面外科硕士研究生30多名,指导博士后和博士生20多名。
科研工作:
主持国家及省部级科研课题15项,资助金额200多万元。其中包括:2011年国家自然科学基金课题—iNOS/NO在癌相关成纤维细胞促进舌鳞癌侵袭转移中的作用机制研究;2011年广东省自然科学基金课题—癌相关成纤维细胞激活一氧化氮合酶信号促进舌鳞癌侵袭转移的作用机制研究和2011年广州市科技计划项目—叶酸预防维甲酸诱导的小鼠腭裂的基因表达谱的的研究。
著作、论文、成果:
近年来发表在SCI期刊源上论文题录(﹡为通信作者,下列文章可来函索取)
65. Wang L, Chen WL﹡. Surgical excision of sialoblastoma in the parotid gland in newborn. Int J Pediatr Otorhinolaryngol. 2013;77(8):1268-71.
64. Chen WL, et al. Osteotomy in the vertical ramus outside the mandibular foramen for tumours in the parapharyngeal space. J Craniomaxillofac Surg. 2013 Jun 18. [Epub ahead of print]
63. Chen WL, et al. Functional hemitongue reconstruction using innervated supraclavicular fasciocutaneous island flaps with the cervical plexus and reinnervated supraclavicular fasciocutaneous island flaps with neurorrhaphy of the cervical plexus and lingual nerve. Head Neck. 2013 Jun 1 [Epub ahead of print]
62. Chen WL, et al. Percutaneous sclerotherapy of sialoceles after parotidectomy with fibrin glue, OK-432, and bleomycin. Br J Oral Maxillofac Surg. 2013 Apr 29. [Epub ahead of print]
61. Wu H, Chen WL﹡. Functional Reconstruction With an Extended Supraclavicular Fasciocutaneous Island Flap Following Ablation of Advanced Oropharyngeal Cancer. J Craniofac Surg. 2012;23(6):1668-71.
60. You YH, Chen WL﹡. Closure of large oropharyngocutaneous fistulas using a folded extensive supraclavicular fasciocutaneous island flap J Oral Maxillofac Surg Med Pathol,2012.09.012 ARTICLE IN PRESS
59. Wei FH, Chen WL﹡. Contralateral Full-thickness Retroangular Flap for the Reconstruction of Midfacial Through-and-through Defects Following Skin Cancer Ablation. Chin J Dent Res. 2012;15(1):21-4.
58. Li JS, Chen WL﹡. Extracapsular dissection of pleomorphic adenoma of the parotid gland through minimal preauricular and retroauricular incisions in children. J Craniofac Surg. 2012;23(3):661-3.
57. Li HG, Han JJ, Huang ZQ, Wang L, Chen WL﹡. IMP3 Is a Novel Biomarker to Predict Metastasis and Prognosis of Tongue Squamous Cell Carcinoma. J Craniofac Surg. 2011;22(6):2022-5.
55. Chen WL, et al. Double mental neurovascular v-y island advancement flaps combined with tongue flaps for functionally reconstructing total lower-lip defects. J Craniofac Surg. 2012;23(1):181-3.
54. Fan S, Tang QL, Lin YJ, Chen WL﹡. A review of clinical and histological parameters associated with contralateral neck metastases in oral squamous cell carcinoma. Int J Oral Sci. 2011;3(4):180-91.
53. Chen WL, et al. Reconstruction of Major Full Cheek Defects With Combined Extensive Pedicled Supraclavicular Fasciocutaneous Island Flaps and Extended Vertical Lower Trapezius Island Myocutaneous Flaps After Ablation of Advanced Oral Cancer. J Oral Maxillofac Surg. 2012;70(5):1224-31.
52. You YH, Chen WL﹡. SMAS fold flap and allograft dermal matrix repairing parotid bed following parotidectomy to prevent facial deformity and Frey's syndrome. Asian J Oral Maxillofac Surg. 2012, 24(1):18-22
51. Tang QL, Chen WL﹡. Expression and significance of Cyr61 in distant metastasis cells of human primary salivary adenoid cystic carcinoma Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(2):228-36.
50. Chai Q, Chen WL﹡. Preliminary Experiences in Treating Infantile Hemangioma With Propranolol. Ann Plast Surg. 2011 May 27. [Epub ahead of print]
49. Chen WL, et al. Maxillary Functional Reconstruction Using a Reverse Facial Artery–Submental Artery Mandibular Osteomuscular Flap with Dental Implants. J Oral Maxillofac Surg, 2011;69(11):2909-14.
48. Tang QL, Fan S, Li HG, Chen WL﹡. Expression of Cyr61 in primary salivary adenoid cystic carcinoma and its relation to Ki-67 and prognosis. Oral Oncol. 2011;47(5):365-70.
47. Zhen Y, Wang JG, Tao D, Wang HJ, Chen WL﹡. Efficacy survey of swallowing function and quality of life in response to therapeutic intervention following rehabilitation treatment in dysphagic tongue cancer patients. Eur J Oncol Nurs. 2012;16(1):54-8.
46. Wang YY, Chen WL﹡. Expression of the membrane-cytoskeletal linker Ezrin in salivary gland adenoid cystic carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112(1):96-104.
45. Chen WL, et al. Percutaneous sclerotherapy of massive macrocystic lymphatic malformations of the face and neck using fibrin glue with OK-432 and bleomycin. Int J Oral Maxillofac Surg. 2011;40(6):572-6.
44. Fan S, Chen WL﹡. Concerns about anesthetizing palatal tissues. J Oral Maxillofac Surg. 2011;69(2):574.
43. Chen WL, et al. Mandible reconstructed with mandibular osteomuscular and facial-cervico-pectoral flap. Asian J Oral Maxillofac Surg. 2011;(23):69-72
42. Chen WL, et al. Use of the contralateral retroangular island flap for reconstructing midfacial defects after skin cancer ablation. Head Neck. 2011;33(12):1765-8.
41.Wang JG, Chen WL﹡. Reverse facial artery-submental artery deepithelialised submental island flap to reconstruct maxillary defects following cancer ablation. J Craniomaxillofac Surg. 2011;39(7):499-502.
40.Huang ZQ, Chen WL﹡. Extracellular matrix metalloproteinase inducer expression in salivary gland tumors: a correlation with microvessel density. J Craniofac Surg. 2010;21(6):1855-60.
39.Chen WL, Zhang DM, Yang ZH, Huang ZQ, Wang JG, Zhang B, Li JS. Extended supraclavicular fasciocutaneous island flap based on the transverse cervical artery for head and neck reconstruction after cancer ablation. J Oral Maxillofac Surg. 2010;68(10):2422-30.
38. Chen WL, et al. A pedicled mandibular osteomuscular flap for reconstructing composite mandibular defects. Oral Surg. 2010;3(1):16-21.
37. Chen WL, et al. Reconstruction of large defects of the neck using an extended vertical lower trapezius island myocutaneous flap following salvage surgery for neck recurrence of oral carcinoma. J Plast Reconstr Aesthet Surg. 2011;64(3):319-22.
36. Zhang B, Wang JG, Chen WL﹡. Reverse facial-submental artery island flap for reconstruction of oropharyngeal defects following middle and advanced-stage carcinoma ablation. Br J Oral Maxillofac Surg. 2011;49(3):194-7
35. You YH, Chen WL﹡. The feasibility of facial-submental artery island myocutaneous flaps for reconstructing defects of the oral floor following cancer ablation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(6):e12-6.
34. Chen WL, et al. Percutaneous sclerotherapy of juvenile nasopharyngeal angiofibroma using fibrin glue combined with OK-432 and bleomycin. Int J Pediatr Otorhinolaryngol. 2010;74(4):422-425.
33. Chen WL, et al. Facial Contour Reconstruction After Benign Tumor Ablation Using Reverse Facial-Submental Artery Deepithelialized Submental Island Flaps. J Craniofac Surg. 2010;21(1):83-86.
32.You YH, Chen WL﹡. Reverse facial-submental artery island flap for the reconstruction of maxillary defects after cancer ablation. J Craniofac Surg. 2009;20(6):2217-20
31. Fan S, Chen WL﹡, et al. Anesthetic efficacy of inferior alveolar nerve block plus buccal infiltration or periodontal ligament injections with articaine in patients with irreversible pulpitis in the mandibular first molar. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108(5):e89-93.
30. Chen WL, et al. Percutaneous sclerotherapy of massive venous malformations of the face and neck using fibrin glue combined with OK-432 and pingyangmycin. Head Neck. 2010,32(4):467-472.
29. Li HG, Li JS, Chen WL﹡, et al. Prognostic significance of erythropoietin and erythropoietin receptor in tongue squamous cell carcinoma. Br J Oral Maxillofac Surg. Br J Oral Maxillofac Surg. 2009;47(6):470-5. Epub 2009 Jun 25.
28. Chen WL, et al. Submental flap for reconstructing tongue defect with V-Y advancement flap for repairing submental defect. Otolaryngol Head Neck Surg. 2009;141(2):202-206.
27. Chen WL, et al. A multidisciplinary approach to treating maxillofacial arteriovenous malformations in children. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108(1):41-47.
26. Chen WL, et al. Surgical excision of cervicofacial giant macrocystic lymphatic malformations in infants and children. Int J Pediatr Otorhinolaryngol. 2009;73(6):833-7.
25. Yan L, Chen WL﹡, et al. Inhibition of VEGF expression in tongue squamous cancer cells via RNA interference silencing of iNOS gene. Int J Oral Maxillofac Surg. 2009,38(4):369-373.
24. Li JS, Chen WL﹡, et al. Pediatric Mandibular Reconstruction After Benign Tumor Ablation Using a Vascularized Fibular Flap. J Craniofac Surg. 2009,20(2):431-434
23. Chen WL, et al. The trapezius osteomyocutaneous island flap for reconstructing hemimandibular and oral defects following the ablation of advanced oral malignant tumors. J Craniomaxillofac Surg. 2009,37(2):91-95.
22. Chen WL, et al. Transplantation of a reverse facial artery pedicled submandibular gland in a dog. Int J Oral Maxillofac Surg. 2008;37(11):1054-8.
21. Chen WL, et al. Reverse facial artery-submental artery mandibular osteomuscular flap for the reconstruction of maxillary defects following the removal of benign tumors. Head Neck. 2009,31(6):725-731.
20. Fan S, Chen WL﹡, et al. Comparison of the efficiencies of permanent maxillary tooth removal performed with single buccal infiltration versus routine buccal and palatal injection. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009,107(3): 359-363
19. Chen WL, et al. Liquid nitrogen cryotherapy of lip mucosa hemangiomas under inhalation general anesthesia with sevoflurane in early infancy. Ann Plast Surg.2009;62(2):154-7
18. Chen WL, et al. Removal of second branchial cleft cysts using a retroauricular approach. Head Neck. 2009;31(5):695-698.
17. Chen WL, et al. Expression of Inducible Nitric Oxide Synthase and Vascular Endothelial Growth Factor in Ameloblastoma. J Craniofac Surg. 2009;20(1):171-175.
16. Chen WL, et al. Reconstruction with Extended Vertical Lower Trapezius Island Myocutaneous Flap for Total Glossectomy. Chin J Dental Research, 2008,11(1),42-46.
15. Chen WL, et al. Removal of the submandibular gland using a combined retroauricular and transoral approach. J Oral Maxillofac Surg. 2009;67(3):522-7.
14. Chen W, et al. SMAS fold flap and ADM repair of the parotid bed following removal of parotid haemangiomas via pre- and retroauricular incisions to improve cosmetic outcome and prevent Frey's syndrome. J Plast Reconstr Aesthet Surg. 2008;61(8):893-898.
13. Chen WL, et al. Effect of using RNA interference to alter iNOS gene expression on the proliferation of tongue squamous cell carcinoma cell line Tca8113. Br J Oral Maxillofac Surg. 2008,46(6):435-438.
12. Chen WL, et al. Expression and significance of hypoxemia-inducible factor-1alpha in osteosarcoma of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(2):254-257.
11. Chen WL, et al. Reconstruction of the tongue using an extended vertical lower trapezius island myocutaneous flap after removal of advanced tongue cancer. Br J Oral Maxillofac Surg. 2008,46(5):379-382.
10. Chen WL, et al. Two submental island flaps for reconstructing oral and maxillofacial defects following cancer ablation. J Oral Maxillofac Surg. 2008;66(6):1145-56.
9. Chen WL, et al. Extended vertical lower trapezius island myocutaneous flap for repairing extensive oropharyngeal defects. J Oral Maxillofac Surg. 2009;67(6):1349-53.
8. Chen WL, et al. A pilot study on combination compartmentalization and sclerotherapy for the treatment of massive venous malformations of the face and neck. J Plast Reconstr Aesthet Surg. 2008;61(12):1486-92.
7. Chen WL, et al. Pedicled Mandibular Osteomuscular Flap for Zygomatic Reconstruction through a Modified Weber-Ferguson Incision. J Craniofac Surg. 2008; 19(1):235-240.
6. Chen WL, et al. Expression and pathological relevance of inducible nitric oxide synthase in osteosarcoma of the jaws. Int J Oral Maxillofac Surg. 2007;36(6):541-4.
5. Chen WL, et al. Extended vertical lower trapezius island myocutaneous flap in reconstruction of oral and maxillofacial defects after salvage surgery for recurrent oral carcinoma. J Oral Maxillofac Surg. 2007, 65(2):205-11.
4. Chen W, et al. Reconstruction of full cheek defects with combined temporalis myofacial flaps and facial-cervico-pectroral flaps. Oral Surg Oral Med, Oral Pathol Oral Radiol Endod. 2007, 103(1): e10-e15.
3. Chen WL, et al. Extended vertical lower trapezius lsland myocutaneous flap for reconstruction of cranio-maxillofacial defects. Int J Oral Maxillofac Surg. 2007, 36(2):165-70.
2. Chen WL, et al. Recurrent ameloblastoma of the anterior skull base: three cases treated by radical resections. J Craniomaxillofac Surg. 2006;34(7):412-4.
1. Chen WL, et al. Comprehensive treatment of arteriovenous malformations in the oral and maxillofacial region. J Oral Maxillofac Surg, 2005,63(10):1484-1488 0278-2391.
近年来发表在国内核心期刊源上论文题录(﹡为通信作者,下列文章可来函索取)
27. 周斌,陈伟良﹡.癌相关成纤维细胞促口腔鳞状细胞癌侵袭转移的研究进展. 国际口腔医学杂志,2012,39
26. 刘军平,陈伟良﹡. 两种硬化治疗方法对面颈部巨大静脉畸形的疗效比较. 广东牙病防 治,2013,21(6):296-300
25. 梁启祥,陈伟良﹡,等. 双颏神经血管蒂V-Y岛状推进皮瓣联合舌皮瓣功能性重建完 全性下唇缺损.中国口腔颌面外科杂志,2013,11(3):235-237.
24. 李荣盛, 黎江,陈伟良. 逆行面动脉-颏下动脉岛状肌皮瓣修复颊黏膜缺损(附13例报告). 临床口腔医学杂志. 2013. 29(1): 35-36.
23. 王友元,陈伟良﹡, 等. 晚期口腔癌术后颊部大范围洞穿缺损的修复. 中国口腔颌面外科杂志, 2013,11(1):61-65.
22. 刘军平,陈伟良,等. 折叠延长下斜方肌岛状皮瓣修复面颊部巨大洞穿性缺损.中国 口腔颌面外科杂志,2013,11(1):52-55.
21. 周苗,黄志权,柴强,陈伟良﹡,等.纤维蛋白胶联合OK-432和博来霉素经皮硬化治疗头颈部 大囊型淋巴管畸形.中国口腔颌面外科杂志,2012,10(5):432-436
20. 焦九阳,梁衍灿,陈伟良﹡,等. 应用对侧逆行内眦动脉瓣修复面中部皮肤癌术后缺损. 中国口腔颌面外科杂志,2012,10(3):241-244.
19.王磊,陈伟良﹡. 儿童头颈部肉瘤的研究进展. 国际口腔医学杂志,2012,39(增刊1):157-160. 国家自然科学基金资助项目(81172563)
18.梁衍灿,焦九阳,陈伟良﹡,等.下颌骨肌瓣联合面颈胸旋转皮瓣修复下颌骨放射性骨坏死. 中国口腔颌面外科杂志,2012,10(2):151-154
17.Peng GG, Chen WL﹡. Eagle's Syndrome Treated with Dissection of the Styloid Process via an Extraoral Approach Combined with Antidepressants. Chin J Dent Res. 2011;14(1):37-40.
16.王友元,李劲松,陈伟良﹡.埃兹蛋白相关信号通路与肿瘤侵袭转移.国际肿瘤学杂志. 2011;38(3);116-169.
15.张大明, 陈伟良﹡. 延长锁骨上岛状皮瓣在修复舌鳞状细胞癌术后缺损中的应用.中华口腔医学杂志, 2011,46(1):24-26
14.陈伟良, 等. 生物胶联合OK-432和平阳霉素治疗面颈部巨大静脉畸形. 中华口腔颌面外科杂志;2010,8(6):555-557
13.陈伟良,等. 逆行面动脉为蒂的下颌下腺移植的实验研究.中国口腔颌面外科杂志, 2010,8(6)
12.陈伟良, 等. 逆行面动脉-颏下动脉下颌骨肌皮瓣修复上颌骨Brown 2A型缺损. 中国口腔颌面外科杂志, 2010,8(1)43-46.
11.张大明,陈伟良﹡等. 腭部巨大基底细胞腺癌1例报告及文献复习. 中国口腔颌面外科杂志, 2009,7(2):190-192.
10.张大明,陈伟良﹡,等. 斜方肌骨肌皮瓣在修复半侧下颌骨切除及口腔软组织缺损中的应用. 中国口腔颌面外科杂志, 2009,7(4):322-325.
9. Wang YY, Chen WL﹡. Ezrin and inducible nitric oxide synthase in malignant proliferation of salivary gland pleomorphic adenoma. Chin J Cancer. 2009;28(10):1072-6.
8. Chen WL. Deep Plane Cervicofacial Flap for Reconstruction of Large Oncosurgical Defects of the Cutaneous Face and Neck. Chin J Dent Res, 2009,12(1),27-30.
7. Huang ZQ, Li JS, Chen WL﹡. Application of multislice spiral CT and 3D reconstuction in diagnosis and treatment of vascular malformations in head and neck. Zhonghua Zheng Xing Wai Ke Za Zhi. 2009;25(1):28-31.
6. 王友元, 陈伟良﹡, 等. Ezrin在人涎腺腺样囊性癌中的表达及对ACC-M细胞增殖、侵袭活性的影响.中华口腔医学杂志, 2009;44(4):203-207.
5. 陈伟良, 等. 耳后区进路切除第二鳃裂囊肿8例分析. 中国口腔颌面外科杂志. 2009:7(2):176-178.
4. 陈伟良, 等. 横向颈阔肌肌皮瓣和面动脉-颏下动脉岛状肌皮瓣修复颊癌术后缺损. 中国口腔颌面外科杂志. 2008:5(6):156-160.
3. Wang YY, Chen WL﹡. Advancement of molecularly targeted therapies for salivary gland cancers Zhonghua Kou Qiang Yi Xue Za Zhi. 2008;43(12):768-70.
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